Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils.

بررسی فراوانی ژن‌های Necrotizing factor type 1 و Hemolysin در بین سویه‌های اشریشیاکلی جدا شده از بیماران بیمارستان روحانی شهرستان بابل در سال 1396: یک گزارش کوتاه

  Background and Objectives:  Currently, Escherichia coli is considered as one of the main causes of bacterial urinary tract infections. The aim of this study was evaluating the frequency of necrotizing factor type 1 (CNF1) and hemolysin (Hly) genes among E. coli strains isolated from hospitalized patients of Rouhani Hospital in Babol city. Materials and Methods: In this descriptive study, a ...

Subhemolytic doses of Escherichia coli hemolysin evoke large quantities of lipoxygenase products in human neutrophils.

Polymorphonuclear leukocytes (PMN) have been identified as preferred target cells for Escherichia coli hemolysin in human blood (Bhakdi, S., Greulich, S., Muhly, M., Eberspächer, B., Becker, H., Thiele, A., and Hugo, F. (1989) J. Exp. Med. 169, 737-754). Leukotriene and 5-hydroxyeicosatetraenoic acid generation was investigated in human PMN challenged with E. coli hemolysin in the absence or pr...

Bacterial adherence and hemolysin production from Escherichia coli induces histamine and leukotriene release from various cells.

We investigated the role of bacterial adherence and hemolysin production from Escherichia coli parent and genetically cloned strains as to their effects on histamine release from rat mast cells and leukotriene generation from human polymorphonuclear granulocytes. These mediators were involved in the induction of inflammatory disease processes and led, for example, to enhancement of vascular per...

Title: Role of Capsule and Hemolysin in Resistance of Enterotoxigenic Escherichia coli to Porcine Serum and Neutrophils - NPB #99-104 Investigator:

Distribution of Genes Encoding Iron Uptake Systems among the Escherichia coli Isolates from Diarrheal Patients of Iran

Introduction: Diarrheagenic Escherichia coli (DEC) including enteropathogenic (EPEC), enteroaggregative (EAEC), enterotoxigenic (ETEC), and shiga toxin producing E. coli are among the most common agents of diarrhea. There are various classes of iron uptake receptors, but there is not much data on the presence of these iron receptors in DEC isolates. The present study aimed to evaluate the prese...